C # Assign a certain array element to the Button element.

There is a two-dimensional array arr [5, 5] and on the form 25 buttons located 5 by 5 How to match the element of this array to a specific button, that is, when you click on a button, the value of an element in the array (or in neighboring elements) changes? In other words, I want to somehow index the button element so that I can stick it into a loop.